BTNL2 anticorps
Aperçu rapide pour BTNL2 anticorps (ABIN7263105)
Antigène
Voir toutes BTNL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human BTNL2 (NP_062548.1).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- BTNL2 (Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2))
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Autre désignation
- BTNL2
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Sujet
- This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.
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Poids moléculaire
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Observed_MW: 60 kDa
Calculated_MW: 19 kDa/27 kDa/28 kDa/30 kDa/43 kDa/50 kDa
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ID gène
- 56244
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UniProt
- Q9UIR0
Antigène
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