GTF2A2 anticorps

N° du produit ABIN7263683

L’anticorps Lapin Polyclonal anti-GTF2A2 a été validé pour WB. Il convient pour détecter GTF2A2 dans des échantillons de Humain.

Aperçu rapide pour GTF2A2 anticorps (ABIN7263683)

Antigène: GTF2A2 (General Transcription Factor IIA, 2, 12kDa (GTF2A2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTF2A2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GTF2A2 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human GTF2A2 (NP_004483.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GTF2A2

Antigène: GTF2A2 (General Transcription Factor IIA, 2, 12kDa (GTF2A2))

Autre désignation: GTF2A2

Sujet: Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A, MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP, MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF, MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).

Poids moléculaire:

Observed_MW: 12 kDa

Calculated_MW: 12 kDa

ID gène: 2958

UniProt: P52657