MKL1 anticorps

N° du produit ABIN7264553

Détail du produit anti-MKL1 anticorps

Antigène: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MKL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human MKL1 (NP_065882.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MKL1

Antigène: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Autre désignation: MKL1 (MKL1 Produits)

Synonymes: anticorps MKL1, anticorps BSAC, anticorps MAL, anticorps MRTF-A, anticorps Mrtf-a, anticorps mrtf-a, anticorps mrtfa, anticorps AI852829, anticorps AMKL, anticorps AW743281, anticorps AW821984, anticorps Bsac, anticorps Mal, anticorps Mrtf-A, anticorps megakaryoblastic leukemia (translocation) 1, anticorps megakaryoblastic leukemia 1 protein, anticorps megakaryoblastic leukemia (translocation) 1 S homeolog, anticorps MKL (megakaryoblastic leukemia)/myocardin-like 1, anticorps MKL1, anticorps mkl1, anticorps Mkl1, anticorps mkl1.S

Sujet: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 145 kDa

Calculated_MW: 98 kDa

ID gène: 57591

UniProt: Q969V6