CKAP5 anticorps
Aperçu rapide pour CKAP5 anticorps (ABIN7264583)
Antigène
Voir toutes CKAP5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein of human CKAP5 (NP_001008938.1).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))
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Autre désignation
- CKAP5
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Sujet
- This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation, it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Poids moléculaire
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Observed_MW: 250 kDa
Calculated_MW: 218 kDa/225 kDa/226 kDa
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ID gène
- 9793
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UniProt
- Q14008
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Pathways
- M Phase
Antigène
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