BCCIP anticorps

N° du produit ABIN7264637

Cet anticorps anti-BCCIP Polyclonal Lapin (ABIN7264637) détecte spécifiquement BCCIP dans IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCCIP anticorps (ABIN7264637)

Antigène: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCCIP est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-BCCIP anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human BCCIP (NP_510868.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BCCIP

Antigène: BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

Autre désignation: BCCIP

Sujet: This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.

ID gène: 56647

UniProt: Q9P287