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SNX15 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement SNX15 dans IF. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN7264751

Aperçu rapide pour SNX15 anticorps (ABIN7264751)

Antigène

Voir toutes SNX15 Anticorps
SNX15 (Sorting Nexin 15 (SNX15))

Reactivité

  • 35
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 31
  • 3
  • 1
Lapin

Clonalité

  • 33
  • 2
Polyclonal

Conjugué

  • 20
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SNX15 est non-conjugé

Application

  • 22
  • 17
  • 2
  • 2
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • Attributs du produit

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogène

    Recombinant fusion protein of human SNX15 (NP_037438.2).

    Isotype

    IgG
  • Indications d'application

    IF 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    SNX15 (Sorting Nexin 15 (SNX15))

    Autre désignation

    SNX15

    Sujet

    This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

    ID gène

    29907

    UniProt

    Q9NRS6
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