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beta Catenin anticorps (pSer33, pSer37, pThr41)

Name: beta Catenin anticorps (pSer33, pSer37, pThr41)
Brand: antibodies-online
SKU: ABIN7265240
Price: 620 EUR
Availability: InStock

CATNB Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated

Western blot analysis of extracts of 293T cells using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody.

Immunohistochemistry of paraffin-embedded Human colon carcinoma using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody at dilution of 1:100 (40x lens).

IHC (p)

Immunohistochemistry of paraffin-embedded Human skin using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody at dilution of 1:100 (40x lens).

IHC (p)

Immunohistochemistry of paraffin-embedded Rat skin using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody at dilution of 1:100 (40x lens).

IHC (p)

Immunohistochemistry of paraffin-embedded Mouse kidney using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody at dilution of 1:100 (40x lens).

IHC (p)

Immunohistochemistry of paraffin-embedded Human lung cancer using Phospho-β-catenin(S33/S37/T41) Polyclonal Antibody at dilution of 1:100 (40x lens).

IHC (p)

6 images

N° du produit ABIN7265240

Fiche de données

Antigène Voir toutes beta Catenin (CATNB) Anticorps

beta Catenin (CATNB) (Catenin, beta (CATNB))
Épitope
42

27

21

20

19

18

17

17

17

16

16

15

9

8

7

7

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer33, pSer37, pThr41
Reactivité
331

247

225

29

23

22

18

18

5

5

5

5

1

1

1

1

1

1

1

1
Humain, Souris, Rat
Hôte
271

59

4

2

1
Lapin
Anticorps secondaires appropriés
Clonalité
266

71
Polyclonal
Conjugué
123

22

16

15

15

15

15

15

11

10

9

9

9

9

9

8

4

4

4

4

4

4

1

1

1
Cet anticorp beta Catenin est non-conjugé
Application
207

158

120

118

74

63

61

49

36

31

22

8

7

4

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit

Phosphorylated antibody

Purification

Affinity purification

Immunogène

A synthetic phosphorylated peptide around S33 & T41 of human beta Catenin (NP_001091679).

Isotype

IgG

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Indications d'application

WB 1:500-1:2000 IHC 1:50-1:200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20°C. Avoid freeze / thaw cycles.
Antigène

beta Catenin (CATNB) (Catenin, beta (CATNB))

Autre désignation

beta-catenin (CATNB Produits)

Synonymes

anticorps Bfc, anticorps Catnb, anticorps Mesc, anticorps CTNNB, anticorps MRD19, anticorps armadillo, anticorps ctnnb, anticorps id:ibd2058, anticorps wu:fb73e10, anticorps wu:fi81c06, anticorps wu:fk25h01, anticorps beta-catenin, anticorps ctnnb1, anticorps CHBCAT, anticorps catenin (cadherin associated protein), beta 1, anticorps catenin beta 1, anticorps catenin (cadherin-associated protein), beta 1, anticorps catenin beta 1 L homeolog, anticorps Ctnnb1, anticorps CTNNB1, anticorps ctnnb1, anticorps ctnnb1.L

Sujet

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Poids moléculaire

Observed_MW: 85 kDa
Calculated_MW: 9 kDa/85 kDa

ID gène

1499

UniProt

P35222

Pathways

Peptide Hormone Metabolism