POLR2A/RPB1 anticorps (pSer5)

N° du produit ABIN7265278

Cet anticorps Lapin Polyclonal détecte spécifiquement POLR2A/RPB1 dans WB, IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour POLR2A/RPB1 anticorps (pSer5) (ABIN7265278)

Antigène: POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR2A/RPB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-POLR2A/RPB1 anticorps

Épitope: pSer5

Attributs du produit: Phosphorylated antibody

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding S5 of human POLR2A

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur POLR2A/RPB1

Antigène: POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

Autre désignation: POLR2A

Sujet: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

Poids moléculaire:

Observed_MW: 260 kDa

Calculated_MW: 63 kDa/217 kDa

ID gène: 5430

UniProt: P24928

Pathways: Regulatory RNA Pathways