TCR alpha/beta anticorps

N° du produit ABIN7013895

Cet anticorps Souris Monoclonal détecte spécifiquement TCR alpha/beta dans FACS, IP, IHC (fro), WB, IHC (p), Func et ICC. Il présente une réactivité envers Rat et Non-Human Primate.

Aperçu rapide pour TCR alpha/beta anticorps (ABIN7013895)

Antigène: TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))

Reactivité: Rat, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TCR alpha/beta est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Immunocytochemistry (ICC)

Clone: R73

Détail du produit anti-TCR alpha/beta anticorps

Fonction: Anti-Rt TCR alpha/beta Purified Low Endotoxin

Specificité: The mouse monoclonal R73 recognizes an extracellular epitope TCR alpha/beta, the dominant subtype of T cell receptor expressed in peripheral blood.

Purification: Purified by protein-A affinity chromatography.

niveau d'endotoxine: Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Immunogène: Rat T blasts and erythrocytes

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL.
Functional application: In vitro activation and in vivo depletion of alpha/beta TCR T cells.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur TCR alpha/beta

Antigène: TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))

Autre désignation: TCR alpha/beta

Sujet: The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.,TCRA/B