SIGLEC8 anticorps (Extracellular Domain)

N° du produit ABIN7013899

L’anticorps anti-SIGLEC8 Monoclonal Souris est utilisé pour la détection de SIGLEC8 dans des échantillons de Humain. Il a été validé pour IP, ELISA et FACS.

Aperçu rapide pour SIGLEC8 anticorps (Extracellular Domain) (ABIN7013899)

Antigène: SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIGLEC8 est non-conjugé

Application: Immunoprecipitation (IP), ELISA, Flow Cytometry (FACS)

Clone: 7C9

Détail du produit anti-SIGLEC8 anticorps

Épitope: Extracellular Domain

Fonction: Anti-Hu SIGLEC8 Purified

Attributs du produit: The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8, an eosinophil marker, expressed e.g. in lymph nodes and spleen.

Purification: Purified by protein-A affinity chromatography.

Immunogène: Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur SIGLEC8

Antigène: SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

Autre désignation: SIGLEC8

Sujet: Sialic acid binding Ig like lectin 8,SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker, although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum, especially in case of eosinophil-associated diseases.,SAF2

ID gène: 27181

UniProt: Q9NYZ4