HDAC6 anticorps
Aperçu rapide pour HDAC6 anticorps (ABIN7013924)
Antigène
Voir toutes HDAC6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-HDAC6 Purified
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Specificité
- The mouse monoclonal antibody 159 recognizes SE domain of human histone deacetylase 6 (HDAC6, an intracellular antigen), amino acids 971-981.
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Aucune reactivité croisée
- Souris, Poisson zèbre (Danio rerio)
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Purification
- Purified by protein-A affinity chromatography.
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Immunogène
- human HDAC6
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Isotype
- IgG1 kappa
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Indications d'application
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Western blotting: Recommended dilution: 1-5 μg/mL.
Immunocytochemistry: Recommended dilution: 5-10 μg/mL. -
Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Autre désignation
- HDAC6
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Sujet
- Histone deacetylase 6,Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.,Histone deacetylase 6
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ID gène
- 10013
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UniProt
- Q9NSW6
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Antigène
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