CD51/CD61 anticorps

N° du produit ABIN7013947

L’anticorps Souris Monoclonal anti-CD51/CD61 a été validé pour FACS, IP et IHC (fro). Il convient pour détecter CD51/CD61 dans des échantillons de Humain et Poulet.

Aperçu rapide pour CD51/CD61 anticorps (ABIN7013947)

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Reactivité: Humain, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD51/CD61 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 23C6

Détail du produit anti-CD51/CD61 anticorps

Fonction: Anti-Hu CD51/CD61 Purified

Specificité: The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex, that is expressed mainly on human osteoclasts, but also e.g. on placenta, or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.

Aucune reactivité croisée: Boeuf (Vache), Porc, Lapin

Purification: Purified by protein-A affinity chromatography.

Immunogène: A cell suspension containing osteoclasts from osteoclastomas

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 2-6 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur CD51/CD61

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Autre désignation: CD51/CD61

Sujet: CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.,VNRA, MSK8, ITGB3, ITGAV, Integrin alpha5beta3, OFA, VR