ITGA5 anticorps (PE)
Aperçu rapide pour ITGA5 anticorps (PE) (ABIN7013952)
Antigène
Voir toutes ITGA5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Ms CD49e PE
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Attributs du produit
- The rat monoclonal antibody 5H10-27 (MFR5) recognizes an extracellular epitope of murine CD49e, a 135 kDa protein serving as VLA-5 alpha chain, expressed on thymocytes, activated T cells, splenic B cells, and mast cells.
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Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Immunogène
- C57BL/6 x A/J)F1 murine mast cell line
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Isotype
- IgG2a, kappa
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Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze,Protect from prolonged exposure to light
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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Autre désignation
- CD49e
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Sujet
- Integrin alpha 5,CD49e, the alpha 5 integrin, noncovalently associates with the beta 1integrin (CD29) to form VLA-5 integrin complex. CD49e itself is composed of two disulfide-linked chains of 135 kDa and 25 kDa. VLA-5 binds to RGD sequence of fibronectin, and to neural adhesion molecule L1. It is important in maintaining the integrity of endothelial monolayers, in monocyte migration into the extracellular tissues, and it also provides a co-stimulatory signal to T cells and enhances receptor and complement receptor-mediated phagocytosis.,ITGA5, VLA-5 alpha, FNRA
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ID gène
- 16402
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UniProt
- P11688
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Pathways
- Integrin Complex
Antigène
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