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CD2 anticorps (PE)

CD2 Reactivité: Souris FACS Hôte: Rat Monoclonal RM2-5 PE
N° du produit ABIN7013991
  • Antigène Voir toutes CD2 Anticorps
    CD2
    Reactivité
    • 164
    • 42
    • 18
    • 15
    • 12
    • 10
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 135
    • 44
    • 29
    • 1
    Rat
    Clonalité
    • 164
    • 43
    • 2
    Monoclonal
    Conjugué
    • 88
    • 25
    • 22
    • 17
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD2 est conjugé à/à la PE
    Application
    • 148
    • 52
    • 51
    • 36
    • 34
    • 33
    • 21
    • 13
    • 11
    • 10
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    murine thymocytes
    Clone
    RM2-5
    Isotype
    IgG2b lambda
    Top Product
    Discover our top product CD2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    CD2
    Autre désignation
    CD2 (CD2 Produits)
    Synonymes
    anticorps CD2, anticorps LFA-2, anticorps Ly-37, anticorps Ly37, anticorps SRBC, anticorps T11, anticorps CD2R, anticorps LFA2, anticorps OX-34, anticorps OX34, anticorps CD2 molecule, anticorps CD2 antigen, anticorps Cd2 molecule, anticorps CD2, anticorps Cd2
    Sujet
    CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,LFA-2, Ly37, Ly-37
    ID gène
    12481
    UniProt
    P08920
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