Mu Opioid Receptor 1 anticorps (AA 165-270)

N° du produit ABIN701755

Cet anticorps Lapin Polyclonal détecte spécifiquement Mu Opioid Receptor 1 dans WB, IHC (p), IF (p), ICC, IHC (fro) et IF (cc). Il présente une réactivité envers Souris et Rat et a été mentionné dans 2+ publications.

Aperçu rapide pour Mu Opioid Receptor 1 anticorps (AA 165-270) (ABIN701755)

Antigène: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mu Opioid Receptor 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-Mu Opioid Receptor 1 anticorps

Épitope: AA 165-270

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human mu Opioid receptor

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Mu Opioid Receptor 1 (ABIN701755)

Wu, Li, Wu: "The effect of chronic intermittent hypoxia on respiratory sensitivity to morphine in rats." dans: Sleep & breathing = Schlaf & Atmung, Vol. 21, Issue 1, pp. 227-233, (2017) (PubMed).

Laureano, Dalle Molle, Alves, Luft, Desai, Ross, Silveira: "Intrauterine growth restriction modifies the hedonic response to sweet taste in newborn pups - Role of the accumbal μ-opioid receptors." dans: Neuroscience, Vol. 322, pp. 500-8, (2016) (PubMed).

Détails sur Mu Opioid Receptor 1

Antigène: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Autre désignation: mu Opioid receptor

Sujet:

Synonyms: MOP, MOR, LMOR, MOR1, OPRM, M-OR-1, Mu-type opioid receptor, MOR-1, Mu opiate receptor, Mu opioid receptor, hMOP, OPRM1

Background: This gene encodes one of at least three opioid receptors in humans, the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]

ID gène: 4988

UniProt: P35372

Pathways: cAMP Metabolic Process, Synaptic Membrane