Aquaporin 5 anticorps (Intracellular)

N° du produit ABIN7042941

Cet anticorps anti-Aquaporin 5 est un anticorps Lapin Polyclonal détectant Aquaporin 5 dans WB, IHC, IF et IC. Adapté pour Rat.

Aperçu rapide pour Aquaporin 5 anticorps (Intracellular) (ABIN7042941)

Antigène: Aquaporin 5 (AQP5)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aquaporin 5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)

Détail du produit anti-Aquaporin 5 anticorps

Épitope: AA 251-265, Intracellular

Fonction: A Rabbit Polyclonal Antibody to Aquaporin 5 Channel

Specificité: Intracellular, C-terminus

Réactivité croisée: Humain, Souris, Rat

Homologie: Mouse - identical, human - 10,16 amino acid residues identical

Attributs du produit: Anti-Aquaporin 5 Antibody (ABIN7042941, ABIN7045200 and ABIN7045201) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunocytochemistry and immunohistochemistry applications. It has been designed to recognize AQP5 from mouse, rat, and human samples.

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)DHREERKKTIELTAH corresponding to amino acid residues 251-265 of rat AQP5

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: 1:200

Commentaires:

Cited Application: IHC|ICC|Whole Tissue Staining

Negative Control: (ABIN7234767)

Blocking Peptide: (ABIN7234767)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur Aquaporin 5

Antigène: Aquaporin 5 (AQP5)

Autre désignation: AQP5

Sujet: AQP5,The importance of the aquaporin water channels was underscored by awarding the 2003 Nobel Prize in Chemistry to Peter Agre "for the discovery of water channels". Today, eleven mammalian proteins that belong to the aquaporin family have been identified. The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. Aquaporin 5 (AQP5) is expressed in secretory glands, lung and eye, where it works in modulating the rate of fluid release. Since a number of pathological conditions including pulmonary edema, respiratory distress syndrome and congestive heart failure are characterized by disrupted fluid transport, it has been suggested that modulation of the expression of AQP5 could be a novel modality of treatment of the above illnesses. Indeed, several studies have shown that AQP5 expression is downregulated in animal models of acute lung infection.

Alternative names: Aquaporin 5, AQP5

ID gène: 25241

NCBI Accession: NM_001651

UniProt: P47864