AQP9 anticorps (Intracellular)

N° du produit ABIN7042945

Cet anticorps Lapin Polyclonal détecte spécifiquement AQP9 dans WB et IHC. Il présente une réactivité envers Rat.

Aperçu rapide pour AQP9 anticorps (Intracellular) (ABIN7042945)

Antigène: AQP9 (Aquaporin 9 (AQP9))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AQP9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-AQP9 anticorps

Épitope: AA 4-19, Intracellular

Fonction: A Rabbit Polyclonal Antibody to Aquaporin 9 Channel

Specificité: Intracellular, N-terminus

Réactivité croisée: Souris, Rat

Réactivité croisée (Details): Unlikely to recognize human samples.

Homologie: Mouse - 13,16 amino acid residues identical

Attributs du produit: Anti-Aquaporin 9 Antibody (ABIN7042945 and ABIN7045206) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize AQP9 from mouse and rat samples.

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)EKDGAKKSLMQRLALK, corresponding to amino acid residues 4-19 of rat AQP9

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100

Application Dilutions Western blot wb: 1:200

Commentaires:

Cited Application: IHC

Negative Control: (ABIN7234783)

Blocking Peptide: (ABIN7234783)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur AQP9

Antigène: AQP9 (Aquaporin 9 (AQP9))

Autre désignation: AQP9

Sujet: AQP9, Aquaglyceroporin-9,Aquaporin 9 (AQP-9) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes.1 The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permability characteristics: the aquaporins that are permeated primarily by water (AQP-1, AQP-2, AQP4, AQP-5, AQP-6, AQP-8), and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-3, AQP-7, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores.2AQP-9 is expressed in several tissues including the brain, liver, testis and spleen. In the liver AQP-9 has a central role in glycerol metabolism as demonstrated in experiments using AQP-9 knockout mice: mice deficient in AQP-9 expression showed enhanced plasma levels of glycerol and triglycerides.3

Alternative names: Aquaporin 9, AQP9, Aquaglyceroporin-9

ID gène: 65054

NCBI Accession: NM_020980

UniProt: P56627