Chloride Channel 5 anticorps (Extracellular)

N° du produit ABIN7043053

Cet anticorps Lapin Polyclonal détecte spécifiquement Chloride Channel 5 dans WB et IHC. Il présente une réactivité envers Rat.

Aperçu rapide pour Chloride Channel 5 anticorps (Extracellular) (ABIN7043053)

Antigène: Chloride Channel 5 (CLCN5)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Chloride Channel 5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Chloride Channel 5 anticorps

Épitope: AA 401-415, Extracellular

Fonction: A Rabbit Polyclonal Antibody to CLC-5 (CLCN5) Channel

Specificité: Extracellular

Réactivité croisée: Souris, Rat

Homologie: Mouse - identical, human - 14,15 amino acid residues identical

Attributs du produit: Anti- Antibody (ABIN7043053 and ABIN7044124) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize from human, mouse, and rat samples.

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: CDYENHFNTSKGGEL, corresponding to amino acid residues 401-415 of rat CLCN5 

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: 1:200

Commentaires:

Negative Control: (ABIN7235090)

Blocking Peptide: (ABIN7235090)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur Chloride Channel 5

Antigène: Chloride Channel 5 (CLCN5)

Autre désignation: CLCN5

Sujet: CLCN5, Chloride channel 5, Chloride transporter ClC-5, H+/Cl- exchange transporter 5, DENTS,CLC5 is a member of the voltage-dependent Cl- channel family that includes nine known members. Based on sequence similarity, CLC5 is closely linked to the CLC3 and CLC4 subunits. CLC-5 is mainly found in intracellular vesicles, particularly in early endosomes, where it is believed to contribute to their acidification.The channel is mainly expressed in the kidney, although it has also been found in the small intestine, brain and liver.Mutations in the CLC5 gene cause Dent's disease, an X-linked renal disorder.

Alternative names: CLC-5, CLCN5, Chloride channel 5, Chloride transporter ClC-5, H+/Cl- exchange transporter 5, DENTS

ID gène: 25749

NCBI Accession: NM_000084

UniProt: P51796