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GPR174 anticorps (Extracellular)

Cet anticorps anti-GPR174 est un anticorps Lapin Polyclonal détectant GPR174 dans WB, FACS et LCI. Adapté pour Humain.
N° du produit ABIN7043151

Aperçu rapide pour GPR174 anticorps (Extracellular) (ABIN7043151)

Antigène

Voir toutes GPR174 Anticorps
GPR174 (G Protein-Coupled Receptor 174 (GPR174))

Reactivité

  • 30
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 30
Lapin

Clonalité

  • 30
Polyclonal

Conjugué

  • 20
  • 3
  • 2
  • 2
  • 2
  • 1
Cet anticorp GPR174 est non-conjugé

Application

  • 20
  • 16
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Live Cell Imaging (LCI)
  • Épitope

    • 9
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-175, Extracellular

    Fonction

    A Rabbit Polyclonal Antibody to GPR174

    Specificité

    2nd extracellular loop.

     Réactivité croisée

    Humain, Souris, Rat

    Homologie

    Human - 15,16 amino acid residues identical, mouse,rat - 13

    Attributs du produit

    Anti-GPR174 (extracellular) Antibody (ABIN7043151, ABIN7044455 and ABIN7044456) is a highly specific antibody directed against an epitope of the human receptor. The antibody can be used in western blot and indirect flow cytometry applications. It has been designed to recognize GPR174 from human, mouse, and rat samples.

    Purification

    Affinity purified on immobilized antigen.

    Immunogène

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)DTSGNRTK(S)FVDLPTR, corresponding to amino acid residues 160 - 175 of human GPR174

    Isotype

    IgG
  • Indications d'application

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

    Application Dilutions Western blot wb: 1:400

    Commentaires

    Negative Control: (ABIN7235384)

    Blocking Peptide: (ABIN7235384)

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    0.2 mL double distilled water (DDW).

    Concentration

    1 mg/mL

    Buffer

    PBS pH 7.4

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • Antigène

    GPR174 (G Protein-Coupled Receptor 174 (GPR174))

    Autre désignation

    GPR174

    Sujet

    G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79,GPR174 (LysoPS, LYPSR3), is one of three lysophosphatidyl serine receptors, belonging to the superfamily of G-protein coupled receptors. Lysophospholipids are a diverse group of small, membrane-derived phospholipids that act as extracellular signals1.Activation of GPR174 leads to an increase in cAMP cellular levels, leading to cellular morphological changes, cell to cell adhesion, and delays in cell proliferation2.GPR174 is reported to be a genetic risk locus for Graves disease, an autoimmune disorder that causes hyperthyroidism3 and as a negative regulator of T-cells activation4.

    Alternative names: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79

    ID gène

    84636

    NCBI Accession

    NM_032553

    UniProt

    Q9BXC1
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