GLRA3 anticorps (AA 355-368)

N° du produit ABIN7043258

L’anticorps Lapin Polyclonal anti-GLRA3 a été validé pour WB et IHC. Il convient pour détecter GLRA3 dans des échantillons de Rat.

Aperçu rapide pour GLRA3 anticorps (AA 355-368) (ABIN7043258)

Antigène: GLRA3 (GLRa3) (Glycine Receptor, alpha 3 (GLRa3))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLRA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GLRA3 anticorps

Épitope: AA 355-368

Fonction: A Rabbit Polyclonal Antibody to Glycine Receptor α3

Specificité: 2nd intracellular loop

Réactivité croisée: Humain, Souris, Rat

Homologie: Mouse,human - identical

Attributs du produit: Anti-Glycine Receptor alpha3 Antibody is directed against an epitope of the rat glycine receptor α3. Anti-Glycine Receptor α3 Antibody (ABIN7043258 and ABIN7044396) can be used in western blot and immunohistochemistry applications. It has been designed to recognize GlyRα3 from rat, mouse and human samples.

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)KNKTEAFALEKFYR, corresponding to amino acid residues 355-368 of rat GlyRalpha3

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300

Application Dilutions Western blot wb: 1:200

Commentaires:

Cited Application: IHC

Negative Control: (ABIN7235717)

Blocking Peptide: (ABIN7235717)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur GLRA3

Antigène: GLRA3 (GLRa3) (Glycine Receptor, alpha 3 (GLRa3))

Autre désignation: GLRA3

Sujet: Glycine receptor subunit alpha-3, GLRA3, GlyRα3,Glycine is a major neurotransmitter in the mammalian central nervous system.1 The glycine receptor is a ligand gated Cl- channel, mediating synaptic inhibition in the spinal cord, retina and regions of the brain.2The glycine receptor is a pentamer consisting of α and β subunits. To date there are four known α-subunit isoforms (α1-α4) encoded by different genes.2-4 In humans, two alternative splice variants of the glycine receptor α3 have been described: α3L and α3K, where the α3L splice variant bears an additional segment of 15 amino acids within the long cytoplasmic TM3-4 loop. These variants differ in their desensitization kinetics.3

Alternative names: Glycine Receptor alpha3, Glycine receptor subunit alpha-3, GLRA3, GlyRalpha3

ID gène: 114516

NCBI Accession: NM_001042543

UniProt: P24524