GAP43 anticorps (AA 205-218)

N° du produit ABIN7043263

Cet anticorps Lapin Polyclonal détecte spécifiquement GAP43 dans WB, IHC et IF. Il présente une réactivité envers Rat.

Aperçu rapide pour GAP43 anticorps (AA 205-218) (ABIN7043263)

Antigène: GAP43 (Growth Associated Protein 43 (GAP43))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAP43 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GAP43 anticorps

Épitope: AA 205-218

Fonction: A Rabbit Polyclonal Antibody to GAP43

Specificité: C-terminus

Réactivité croisée: Souris, Rat

Homologie: Mouse - identical, human - 13,14 amino acid residues identical

Attributs du produit: Anti-GAP43 Antibody (ABIN7043263, ABIN7044662 and ABIN7044663) is a highly selective antibody directed against an epitope of rat Neuromodulin. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize GAP43 from human, mouse, and rat samples.

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)KPKESARQDEGKED, corresponding to amino acid residues 205-218 of rat GAP43

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200

Application Dilutions Western blot wb: 1:400

Commentaires:

Negative Control: (ABIN7235735)

Blocking Peptide: (ABIN7235735)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur GAP43

Antigène: GAP43 (Growth Associated Protein 43 (GAP43))

Autre désignation: GAP43

Sujet: Axonal membrane protein GAP-43, Growth-associated protein 43, Neuromodulin, Neural phosphoprotein B-50,Growth associated protein 43 (GAP43) is a neuron specific phosphoprotein that plays an important role in the process of nerve growth, development, regeneration and axonal remodeling. GAP43 belongs to the calmodulin-binding protein family and is highly distributed in the presynaptic membrane1.GAP43 is expressed in developing neurons, especially in the growth cone. In mature neurons, GAP43 is detected in regenerating nerves. In brain injury, neurons exhibit sprouting of the lateral branches and responsive regeneration of the axon accompanied by increased expression of GAP43. GAP43 expression is used as an important tool for evaluating axon injury and the regenerative response in the mature central nervous system (CNS)1,2.

Alternative names: GAP43, Axonal membrane protein GAP-43, Growth-associated protein 43, Neuromodulin, Neural phosphoprotein B-50

ID gène: 29423

NCBI Accession: NM_002045

UniProt: P07936