NMUR1 anticorps (Extracellular)

N° du produit ABIN7043365

Cet anticorps Lapin Polyclonal détecte spécifiquement NMUR1 dans WB, FACS, IHC et LCI. Il présente une réactivité envers Rat.

Aperçu rapide pour NMUR1 anticorps (Extracellular) (ABIN7043365)

Antigène: NMUR1 (Neuromedin U Receptor 1 (NMUR1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMUR1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Live Cell Imaging (LCI)

Détail du produit anti-NMUR1 anticorps

Épitope: AA 316-331, Extracellular

Fonction: A Rabbit Polyclonal antibody to NMUR1 (extracellular)

Specificité: Extracellular, 3rd loop.

Réactivité croisée: Humain, Souris, Rat

Homologie: Human - 12 out of 16 amino acid residues identical, Mouse - 10 out of 16 amino acid residues identical

Attributs du produit: A rabbit polyclonal antibody to NMUR1 (extracellular)

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)DRLMWSMVSHWTDGLR, corresponding to amino acid residues 316 - 331 of rat NMUR1

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300

Application Dilutions Western blot wb: 1:400-1:500

Commentaires:

Negative Control: (ABIN7236064)

Blocking Peptide: (ABIN7236064)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur NMUR1

Antigène: NMUR1 (Neuromedin U Receptor 1 (NMUR1))

Autre désignation: NMUR1

Sujet: Neuromedin-U Receptor 1, G Protein-Coupled Receptor 66, GPR66,Neuromedin U Receptor 1 (NMUR1) is one of the two receptors for the neuropeptide Neuromedin U (NMU). NMUR1 and the second receptor NMUR2 are members of the G protein coupled receptors (GPCRs) superfamily 1.NMU is a neuropeptide with potent activity on smooth muscles that is widely distributed in the gut and central nervous system. NMU interaction with one of its two receptors- NMU1R or NMU2R, mediates the stimulation of smooth muscles, increase of blood pressure, alteration of ion transport in the gut, control of local blood flow and regulation of adrenocortical function1-2.NMU1R is abundantly expressed in peripheral tissues including lung, GI tract, pancreatic islets, testis, adipose, immune tissues, and dorsal root ganglia2, and due to its diverse functions it is a very appealing drug and research candidate.

Alternative names: Neuromedin-U Receptor 1, G Protein-Coupled Receptor 66, GPR66

ID gène: 65276

NCBI Accession: NM_006056

UniProt: Q9JJI5