NMUR1 anticorps (Extracellular, Loop 3)

N° du produit ABIN7886649

Cet anticorps Lapin Polyclonal détecte spécifiquement NMUR1 dans WB, FACS, IHC et LCI. Il présente une réactivité avec des échantillons de Rat.

Aperçu rapide pour NMUR1 anticorps (Extracellular, Loop 3) (ABIN7886649)

Antigène: NMUR1 (Neuromedin U Receptor 1 (NMUR1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMUR1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Live Cell Imaging (LCI)

Détail du produit anti-NMUR1 anticorps

Épitope: AA 316-331, Extracellular, Loop 3

Fonction: A Rabbit Polyclonal antibody to NMUR1 (extracellular)

Réactivité croisée: Humain, Souris, Rat

Homologie: Human - 12 out of 16 amino acid residues identical, Mouse - 10 out of 16 amino acid residues identical

Attributs du produit: A rabbit polyclonal antibody to NMUR1 (extracellular)

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)DRLMWSMVSHWTDGLR, corresponding to amino acid residues 316 - 331 of rat NMUR1

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:400-1:500

FC: 2.5 μg per reaction

ICC: The optimal concentration should be determined by the user

IHC: 1:300

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7236064)

Blocking Peptide: (ABIN7236064)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur NMUR1

Antigène: NMUR1 (Neuromedin U Receptor 1 (NMUR1))

Autre désignation: NMUR1

Sujet:

Synonyms: Neuromedin-U Receptor 1, G Protein-Coupled Receptor 66, GPR66

Description: Neuromedin U Receptor 1 (NMUR1) is one of the two receptors for the neuropeptide Neuromedin U (NMU). NMUR1 and the second receptor NMUR2 are members of the G protein coupled receptors (GPCRs) superfamily 1.NMU is a neuropeptide with potent activity on smooth muscles that is widely distributed in the gut and central nervous system. NMU interaction with one of its two receptors- NMU1R or NMU2R, mediates the stimulation of smooth muscles, increase of blood pressure, alteration of ion transport in the gut, control of local blood flow and regulation of adrenocortical function1-2.NMU1R is abundantly expressed in peripheral tissues including lung, GI tract, pancreatic islets, testis, adipose, immune tissues, and dorsal root ganglia2, and due to its diverse functions it is a very appealing drug and research candidate.

ID gène: 65276

NCBI Accession: NM_006056

UniProt: Q9JJI5