NPTXR anticorps (C-Term, Extracellular)

N° du produit ABIN7043370

Cet anticorps anti-NPTXR Polyclonal Lapin (ABIN7043370) détecte spécifiquement NPTXR dans WB, IHC, FACS et LCI. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour NPTXR anticorps (C-Term, Extracellular) (ABIN7043370)

Antigène: NPTXR (Neuronal Pentraxin Receptor (NPTXR))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPTXR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Live Cell Imaging (LCI)

Détail du produit anti-NPTXR anticorps

Épitope: AA 162-176, C-Term, Extracellular

Fonction: A Rabbit Polyclonal Antibody to NPTXR (extracellular)

Réactivité croisée: Humain, Souris, Rat

Homologie: Rat - identical, human - 14 out of 15 amino acid residues identical

Attributs du produit: Anti-Neuronal Pentraxin Receptor (NPTXR)(extracellular) Antibody (ABIN7043370, ABIN7044746 and ABIN7044747) is a highly specific antibody directed against an extracellular epitope of the mouse NPTXR. The antibody can be used in western blot and immunohistochemistry. It has been designed to recognize NPTXR from mouse, rat and human samples.

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)RGLQDAGPRRDTMAD, corresponding to amino acid residues 162 - 176 of mouse NPTXR 

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:400

FC: 5 μg per reaction

ICC: The optimal concentration should be determined by the user

IHC: 1:1200

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7236082)

Blocking Peptide: (ABIN7236082)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur NPTXR

Antigène: NPTXR (Neuronal Pentraxin Receptor (NPTXR))

Autre désignation: NPTXR

Sujet:

Synonyms: NPR, NPTXR

Description: Neuronal Pentraxin Receptor (NPTXR) belongs to the Pentraxin superfamily of proteins (NP) that is characterized by a pentraxin domain at the C-terminal end. It is the only pentraxin family member anchored to the cell membrane by a putative N-terminal transmembrane domain, as opposed to the other two family members, Neuronal Pentraxin1 (NP1) and Neuronal Pentraxin 2 (NP2) that are secreted proteins. NPs can form homo pentamers and hetero pentamers via their pentraxin domains 1.NPTXR was first identified as the receptor for the snake venom toxin taipoxin and was later found to bind to AMPARs at excitatory synapses and play important, roles in the activity-dependent regulation of neural circuits via this binding activity 1.Lately, the levels of NPTXR protein in cerebrospinal fluid has been identified as a novel potential biomarker of Alzheimer's disease progression and could have important utility in assessing treatment success in clinical trials 2. In addition, NPTXR was identified as a molecule required for gastric cancer metastasis 3.

ID gène: 73340

NCBI Accession: NM_014293

UniProt: Q99J85