SLC28A3 anticorps (Extracellular)

N° du produit ABIN7043709

Cet anticorps anti-SLC28A3 Polyclonal Lapin (ABIN7043709) détecte spécifiquement SLC28A3 dans WB et FACS. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour SLC28A3 anticorps (Extracellular) (ABIN7043709)

Antigène: SLC28A3 (Solute Carrier Family 28 (Sodium-Coupled Nucleoside Transporter), Member 3 (SLC28A3))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC28A3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-SLC28A3 anticorps

Épitope: AA 432-447, Extracellular

Fonction: A Rabbit Polyclonal Antibody to SLC28A3/CNT3

Specificité: 5th extracellular loop

Réactivité croisée: Humain, Souris, Rat

Homologie: human - 14,16 amino acid residues identical,Mouse - 15

Attributs du produit: Anti-SLC28A3/CNT3 (extracellular) Antibody (ABIN7043709, ABIN7044807 and ABIN7044808) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and indirect live cell flow cytometry. It has been designed to recognize CNT3 from human, rat, and mouse samples.

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: Peptide (C)KITLKNAMKMENGDSR, corresponding to amino acid residues 432 - 447 of rat SLC28A3/CNT3

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: 1:400-1:500

Commentaires:

Negative Control: (ABIN7237037)

Blocking Peptide: (ABIN7237037)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur SLC28A3

Antigène: SLC28A3 (Solute Carrier Family 28 (Sodium-Coupled Nucleoside Transporter), Member 3 (SLC28A3))

Autre désignation: SLC28A3

Sujet: Solute Carrier Family 28 Member 3, Concentrative Na+-Nucleoside Cotransporter 3,Solute carrier family 28 member 3 (SLC28A3, CNT3) is a sodium-dependent, concentrative pyrimidine- and purine-selective transporter. SLC28A3 plays an important role in mediating the cellular entry of a broad array of physiological nucleosides and synthetic anticancer nucleoside analog drugs, in a process that is coupled to the sodium cellular gradient1.CNT3 consists of 13 putative trans-membrane domains and it forms a homo-trimer which is important for its activity as a transporter2,3.SLC28 members are crucial determinants in the response to a variety of anticancer and antiviral nucleoside analogs, as they modulate the entry of these analogs into target tissues. Within this large group of solute carriers, SLC28A is a sub-group which consists of SLC28A1, SLC28A2, and SLC28A3. Of the three members of this sub-family, SLC28A3 has the broadest selectivity and the widest expression profile4.

Alternative names: Solute Carrier Family 28 Member 3, Concentrative Na+-Nucleoside Cotransporter 3, CNT3

ID gène: 140944

NCBI Accession: NM_022127

UniProt: Q8VIH3