SSTR1 anticorps (Extracellular, N-Term)

N° du produit ABIN7043763

Cet anticorps anti-SSTR1 Polyclonal Lapin (ABIN7043763) détecte spécifiquement SSTR1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour SSTR1 anticorps (Extracellular, N-Term) (ABIN7043763)

Antigène: SSTR1 (Somatostatin Receptor 1 (SSTR1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSTR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SSTR1 anticorps

Épitope: AA 26-40, Extracellular, N-Term

Fonction: A Rabbit Polyclonal Antibody to Somatostatin Receptor Type 1

Réactivité croisée: Souris, Rat

Homologie: Mouse - identical, human - 13,15 amino acid residues identical

Attributs du produit: Anti-Somatostatin Receptor Type 1 (extracellular) Antibody (ABIN7043763 and ABIN7045262) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize SSTR1 from rat, mouse, and human samples.

Purification: Affinity purified on immobilized antigen.

Immunogène: CSRGPGSGAADGMEE, corresponding to amino acid residues 26-40 of rat SSTR1

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:1000

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7237232)

Blocking Peptide: (ABIN7237232)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur SSTR1

Antigène: SSTR1 (Somatostatin Receptor 1 (SSTR1))

Autre désignation: SSTR1

Sujet:

Synonyms: SSTR1, SS1R, SRIF-2, SRIF2A

Description: Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain it acts as a neurotransmitter in both a stimulatory and inhibitory manner.1,2Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4 and SSTR5) which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time and tissue-specific manner.2Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in in vivo imaging of tumors that are positive to somatostatin receptors.4

ID gène: 25033

NCBI Accession: NM_001049

UniProt: P28646