STX3 anticorps (Cytosolic, N-Term)

N° du produit ABIN7043795

L’anticorps anti-STX3 Polyclonal Lapin est utilisé pour la détection de STX3 dans des échantillons de Rat. Il a été validé pour WB, IF et IC.

Aperçu rapide pour STX3 anticorps (Cytosolic, N-Term) (ABIN7043795)

Antigène: STX3 (Syntaxin 3 (STX3))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STX3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunochromatography (IC)

Classe de qualité: KO Validated

Détail du produit anti-STX3 anticorps

Épitope: AA 2-16, Cytosolic, N-Term

Fonction: A Rabbit Polyclonal Antibody to Syntaxin 3

Réactivité croisée: Humain, Souris, Rat

Homologie: Mouse,human - identical

Attributs du produit: Anti-Syntaxin 3 Antibody is directed against an epitope of rat Syntaxin 3. Anti-Syntaxin 3 Antibody (ABIN7043795 and ABIN7044652) can be used in western blot and immunocytochemistry applications. It has been designed to recognize Syntaxin 3 from rat, mouse and human samples.

Purification: Affinity purified on immobilized antigen.

Immunogène: KDRLEQLKAKQLTQD(C), corresponding to amino acid residues 2-16 of rat syntaxin 3

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7237343)

Blocking Peptide: (ABIN7237343)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur STX3

Antigène: STX3 (Syntaxin 3 (STX3))

Autre désignation: STX3

Sujet:

Synonyms: STX3

Description: Syntaxin 3 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein superfamily. The family includes 36 members in humans and is characterized by the SNARE motif, an evolutionarily conserved stretch of 60-70 amino acids that are arranged in heptad repeats1,2. SNARE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion1,2.SNAREs can be roughly divided into vesicular (v-SNAREs) and target (t-SNAREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cognate v-/t-SNAREs between two opposing membranes generates trans-SNARE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion.Syntaxin 3, like most SNAREs, is a type IV membrane protein with a relatively large N-terminus containing the SNARE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor1,2.Syntaxin 3 functions as a plasma membrane protein t-SNARE that is involved in epithelial cell polarization. Indeed, Syntaxin 3 is specifically localized in the apical membrane of polarized epithelial cells where it likely has a role in the polarized trafficking of newly synthesized proteins3.

ID gène: 81802

NCBI Accession: NM_004177

UniProt: Q08849

Pathways: Synaptic Vesicle Exocytosis