UTS2R anticorps (2nd Cytoplasmic Loop)

N° du produit ABIN7043874

Cet anticorps anti-UTS2R Polyclonal Lapin (ABIN7043874) détecte spécifiquement UTS2R dans WB et IHC. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour UTS2R anticorps (2nd Cytoplasmic Loop) (ABIN7043874)

Antigène: UTS2R (Urotensin 2 Receptor (UTS2R))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UTS2R est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-UTS2R anticorps

Épitope: 2nd Cytoplasmic Loop, AA 154-167

Fonction: A Rabbit Ployclonal Antibody to Urotensin II Receptor

Homologie: Bovine - identical, human,canine - 13,14 amino acid residues identical

Attributs du produit: Anti-Urotensin II Receptor Antibody is directed against the 2nd cytoplasmic loop of the rat UTS2R. Anti-Urontenisn II Receptor Antibody (ABIN7043874 and ABIN7044242) can be used in western blot and immunohistochemical applications, and recognizes UTS2R in rat samples.

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)RPLDTVQRSKGYRK, corresponding to amino acid residues 154-167 of rat URIIR

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Commentaires:

Cited Application: IHC

Negative Control: (ABIN7237551)

Blocking Peptide: (ABIN7237551)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur UTS2R

Antigène: UTS2R (Urotensin 2 Receptor (UTS2R))

Autre désignation: UTS2R

Sujet:

Synonyms: Urotensin 2 receptor, UR-II-R, UR2R, UTS2R, SENR, GPR14

Description: Urotensin II is a powerful vasoconstrictive substance. The human urotensin II receptor (UR-II-R) was originally isolated as an orphan receptor (GPR14) from neural and sensory tissues.1,2 Urotensin II is expressed in various human tissues such as the CNS, skeletal muscle, smooth muscle, pancreas, and heart.3-5 Binding of urotensin II to the receptor leads to activation of phospholipase C. The resulting increase in intracellular Ca2+ may cause the contraction of vascular smooth muscle. ERK1/2 phophorylation may also be involved in mediating the biological activities of urotensin II.6 Recently, evidence has accumulated indicating that urotensin II is also expressed in various kinds of tumor cells such as adrenal tumors and neuroblastomas. In those cells, urotensin II was reported to stimulate cell growth.7-9

ID gène: 57305

NCBI Accession: NM_018949

UniProt: P49684