UTS2R anticorps (AA 154-167)

N° du produit ABIN7043874

Cet anticorps anti-UTS2R est un anticorps Lapin Polyclonal détectant UTS2R dans WB et IHC. Adapté pour Rat.

Aperçu rapide pour UTS2R anticorps (AA 154-167) (ABIN7043874)

Antigène: UTS2R (Urotensin 2 Receptor (UTS2R))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UTS2R est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-UTS2R anticorps

Épitope: AA 154-167

Fonction: A Rabbit Ployclonal Antibody to Urotensin II Receptor

Specificité: 2nd intracellular loop

Homologie: Bovine - identical, human,canine - 13,14 amino acid residues identical

Attributs du produit: Anti-Urotensin II Receptor Antibody is directed against the 2nd cytoplasmic loop of the rat UTS2R. Anti-Urontenisn II Receptor Antibody (ABIN7043874 and ABIN7044242) can be used in western blot and immunohistochemical applications, and recognizes UTS2R in rat samples.

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)RPLDTVQRSKGYRK, corresponding to amino acid residues 154-167 of rat URIIR

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: 1:200

Commentaires:

Cited Application: IHC

Negative Control: (ABIN7237551)

Blocking Peptide: (ABIN7237551)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur UTS2R

Antigène: UTS2R (Urotensin 2 Receptor (UTS2R))

Autre désignation: UTS2R

Sujet: Urotensin 2 receptor, UR-II-R, UR2R, UTS2R, SENR, GPR14,Urotensin II is a powerful vasoconstrictive substance. The human urotensin II receptor (UR-II-R) was originally isolated as an orphan receptor (GPR14) from neural and sensory tissues.1,2 Urotensin II is expressed in various human tissues such as the CNS, skeletal muscle, smooth muscle, pancreas, and heart.3-5 Binding of urotensin II to the receptor leads to activation of phospholipase C. The resulting increase in intracellular Ca2+ may cause the contraction of vascular smooth muscle. ERK1/2 phophorylation may also be involved in mediating the biological activities of urotensin II.6 Recently, evidence has accumulated indicating that urotensin II is also expressed in various kinds of tumor cells such as adrenal tumors and neuroblastomas. In those cells, urotensin II was reported to stimulate cell growth.7-9

Alternative names: Urotensin II Receptor, Urotensin 2 receptor, UR-II-R, UR2R, UTS2R, SENR, GPR14

ID gène: 57305

NCBI Accession: NM_018949

UniProt: P49684