Recombinant Bax (Active Monomer) (AA 12-24), (AA 3-16) anticorps

N° du produit ABIN7072202

L’anticorps anti-Bax (Active Monomer) Chimeric Lapin est utilisé pour la détection de Bax (Active Monomer) dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC, IP et WB.

Aperçu rapide pour Recombinant Bax (Active Monomer) (AA 12-24), (AA 3-16) anticorps (ABIN7072202)

Antigène: Bax (Active Monomer)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)

Clone: 6A7

Détail du produit

Épitope: AA 3-16, AA 12-24

Fonction: Anti-Bax (active monomer) [6A7], Rabbit IgG, kappa

Specificité: In the presence of nonionic detergent, the antibody avidly binds the monomeric form of Bax, but not Bax complexed with either Bcl-XL or Bcl-2. [6A7 ] Bax antibody only recognizes conformationally changed active Bax.

Réactivité croisée: Souris, Rat

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: KLH conjugated to peptides corresponding to amino acids 3-16 of murine Bax (CGSGEQLGSGGPTSS), amino acids 3-16 of human Bax (CGSGEQPRGGGPTSS), and amino acids 12-24 shared by Bax from both species (CGPTSSEQIMKTGA).

Isotype: IgG kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détail du antigène

Antigène: Bax (Active Monomer)

Sujet: Bcl-2-like protein 4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4

UniProt: Q07812