Recombinant CD8 alpha/lyt-2 anticorps

N° du produit ABIN7072216

Cet anticorps Lapin Chimeric détecte spécifiquement CD8 alpha/lyt-2 dans Dep, FACS, IHC, IHC (fro) et in vivo. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour Recombinant CD8 alpha/lyt-2 anticorps (ABIN7072216)

Antigène: CD8 alpha/lyt-2

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Inconjugué

Application: Depletion (Dep), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)

Clone: YTS 169-4

Détail du produit

Fonction: Anti-CD8 alpha/Lyt-2 [YTS 169.4], Rabbit IgG, kappa

Specificité: This antibody recognises the murine CD8 cell surface antigen expressed by a subset of T lymphocytes.

Attributs du produit:

Original Species of Ab: Rat

Original Format of Ab: IgG2b

Purification: Protein A affinity purified

Immunogène: Murine CD8 (Lyt-2).

Isotype: IgG kappa

Information d'application

Indications d'application: The antibody has been shown to show depleting activity in vivo. Mice have two alleles for CD8, Lyt2.1, and Lyt2.2, which are restricted to certain mouse strains. Lyt2.1, for example, is expressed in the mouse strains CBA, AKR, C3H, and DBA, whereas Lyt2.2 is expressed in the mouse strains BALB/c and C57BL/6 (B/6). YTS 169.4 was originally raised against CBA mouse thymocytes. However, there are publications in which it has been used in C57BL/6 and BALB/c mice, wherein it was used specifically as a pan-reactive Lyt2 reagent (Tavaré et al., 2014, PMID: 24390540).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détail du antigène

Antigène: CD8 alpha/lyt-2

Sujet: Leu2, CD8, CD8A, CD8a molecule, CD8a antigen, Leu2 T-lymphocyte antigen, Lyt-2, Lyt2OKT8, p32T-cell antigen Leu2, T-cell antigen, T cell co-receptor, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, T8 T-cell antigen

UniProt: P01731