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Recombinant Tyrosinase-Related Protein 1 anticorps

Cet anticorps anti-Tyrosinase-Related Protein 1 est un anticorps Lapin Chimeric détectant Tyrosinase-Related Protein 1 dans IF, FACS, WB, ELISA, IHC (fro) et IP. Adapté pour Humain.
N° du produit ABIN7072221

Aperçu rapide pour Recombinant Tyrosinase-Related Protein 1 anticorps (ABIN7072221)

Antigène

Voir toutes Tyrosinase-Related Protein 1 (TYRP1) Anticorps
Tyrosinase-Related Protein 1 (TYRP1)

Type d'anticorp

Recombinant Antibody

Reactivité

  • 140
  • 72
  • 9
  • 8
  • 6
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
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  • 3
  • 3
  • 3
  • 3
  • 2
Humain

Hôte

  • 102
  • 43
  • 1
Lapin

Clonalité

  • 78
  • 67
  • 1
Chimeric

Conjugué

  • 61
  • 10
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé

Application

  • 66
  • 53
  • 39
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  • 25
  • 14
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  • 7
  • 5
  • 4
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  • 1
Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Clone

TA99
  • Fonction

    Anti-TRP-1, gp75 [TA99], Rabbit IgG, kappa

    Specificité

    Binds Tyrosinase-related protein-1 (TRP-1), a 70-75k enzyme located in melanocytes, which are specialized cells that produce a pigment called melanin, helping to stabilize tyrosinase, which is the enzyme responsible for the first step in melanin production and determine the shape of melanosomes, which are the structures in melanocytes where melanin is produced.

    Attributs du produit

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    Purification

    Protein A affinity purified

    Immunogène

    70-75 kDa pigmentation-associated glycoprotein in human melanoma cell lines.

    Isotype

    IgG kappa
  • Indications d'application

    This antibody binds to human and murine TRP-1 and had been under evaluation for the treatment of tumours.

    Commentaires

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    Tyrosinase-Related Protein 1 (TYRP1)

    Autre désignation

    TRP-1, gp75

    Sujet

    Melanoma antigen gp75, 5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, Catalase B, Glycoprotein 75, Tyrosinase-related protein 1, TRP, TRP-1, TRP1

    UniProt

    P17643
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