Recombinant Paxillin (LD4 Motif) (AA 260-278) anticorps

N° du produit ABIN7072303

Cet anticorps Souris Monoclonal détecte spécifiquement Paxillin (LD4 Motif) dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Paxillin (LD4 Motif) (AA 260-278) anticorps (ABIN7072303)

Antigène: Paxillin (LD4 Motif)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Clone: LD4 sAB

Détail du produit

Épitope: AA 260-278

Fonction: Anti-Paxillin (LD4 Motif) [LD4 sAB], Mouse IgG1, kappa

Specificité: The antibody binds specifically to the LD-4 motif of human paxillin with a Kd of 6 nM.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: scFv

Purification: Protein A affinity purified

Immunogène: Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP, peptide sequence: WGGSATRELDELMASLSD.

Isotype: IgG1 kappa

Information d'application

Indications d'application: This antibody binds to the LD4-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

Commentaires:

This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détail du antigène

Antigène: Paxillin (LD4 Motif)

Sujet: PXN

UniProt: P49023