Recombinant Paxillin (LD2 Motif) (AA 141-156) anticorps

N° du produit ABIN7072305

Cet anticorps anti-Paxillin (LD2 Motif) Monoclonal Souris (Clone LD2 sAB) (ABIN7072305) détecte spécifiquement Paxillin (LD2 Motif) dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Paxillin (LD2 Motif) (AA 141-156) anticorps (ABIN7072305)

Antigène: Paxillin (LD2 Motif)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Clone: LD2 sAB

Détail du produit

Épitope: AA 141-156

Fonction: Anti-Paxillin (LD2 Motif) [LD2 sAB], Mouse IgG1, kappa

Specificité: The antibody binds specifically to the LD-2 motif of human paxillin with a Kd of 24 nM.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: scFv

Purification: Protein A affinity purified

Immunogène: Peptide corresponding to paxillin-LD2 motif (residues 141-156) fused to MBP, peptide sequence: NLSELDRLLLELNAVQHNP.

Isotype: IgG1 kappa

Information d'application

Indications d'application: This antibody binds to the LD2-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

Commentaires:

This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détail du antigène

Antigène: Paxillin (LD2 Motif)

Sujet: PXN

UniProt: P49023