Recombinant Discoidin Domain Receptor 1 (Extracellular Domain) anticorps

N° du produit ABIN7072320

Cet anticorps anti-Discoidin Domain Receptor 1 Chimeric Lapin (Clone 3E3) (ABIN7072320) détecte spécifiquement Discoidin Domain Receptor 1 dans BP, ELISA et WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Discoidin Domain Receptor 1 (Extracellular Domain) anticorps (ABIN7072320)

Antigène: Discoidin Domain Receptor 1

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Inconjugué

Application: Blocking Peptide (BP), ELISA, Western Blotting (WB)

Clone: 3E3

Détail du produit

Épitope: Extracellular Domain

Fonction: Anti-Discoidin Domain Receptor 1 [3E3], Rabbit IgG, kappa

Specificité: This antibody binds specifically to the extracellular domain of human DDR1.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2

Purification: Protein A affinity purified

Immunogène: Recombinant human DDR1 extracellular domain.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody binds to human Discoidin Domain Receptor 1, a receptor tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates the attachemnt of the cell to the extracellular matrix. This receptor is required for blastocyst implantation during pregnancy, mammary gland differentiation as well as lactation. It promotes smooth muscle cell migration as well as tumour cell invasion. The antibody acts as an antagonist.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détail du antigène

Antigène: Discoidin Domain Receptor 1

Sujet: DDR1

UniProt: Q08345