Recombinant CD81 anticorps
Aperçu rapide pour Recombinant CD81 anticorps (ABIN7072377)
Antigène
Voir toutes CD81 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-CD81 [1D6], Rabbit IgG, kappa
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Specificité
- This antibody is specific for human CD81, which is expressed on most tissues with the exception of red blood cells and platelets.
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Réactivité croisée
- Chimpanzé, Chévre, Mouton
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Attributs du produit
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Immunogène
- This antibody was produced by immunizing mice with 5A6-aggregated OCI-LY8 B cells.
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Isotype
- IgG kappa
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Indications d'application
- This antibody is a strong inducer of homotypic adhesion in hematolymphoid cells (Levy, 1998). This antibody also has an anti-proliferative effect, and is able to induce growth inhibition of B cell lines. Triggering of CD81 by this antibody induces a significant upregulation of the constituitive release of TNF-α by JY cells, an Eptsein-Barr virus-positive B lymphoblastoid cell line (Altomonte, 1995).
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Commentaires
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD81
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Autre désignation
- CD81
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Sujet
- Tetraspanin-28, TAPA-1, Target of the Antiproliferative Antibody 1, Tspan-28
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UniProt
- P60033
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Pathways
- Inositol Metabolic Process, Hepatitis C
Antigène
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