Recombinant CD37 anticorps

N° du produit ABIN7072379

L’anticorps Lapin Chimeric anti-CD37 a été validé pour FACS, IF, WB, IHC (p) et ICC. Il convient pour détecter CD37 dans des échantillons de Humain.

Aperçu rapide pour Recombinant CD37 anticorps (ABIN7072379)

Antigène: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD37 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Clone: MB-1

Détail du produit anti-CD37 anticorps

Fonction: Anti-CD37 [MB-1], Rabbit IgG, kappa

Specificité: This antibody is specific for human CD37, which is expressed on virtually all mature B lymphocytes, but not on pro-B or plasma cells. CD37 is highly expressed on all forms of B cell non-Hodgkin lymphoma, chronic lymphocyte leukemia, and other leukemias. CD37 does not appear to be expressed on T cells, thymocytes, granulocytes or platelets.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: BALB/c mice were immunized with lymph node cells from a patient with nodular poorly differentiated lymphocytic lymphoma. Immunophenotyping studies of these cells identified them as B cells expressing SIgG/lambda, as well as HLA-DR. Leu-12, and B1.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody recognizes human CD37, and has been used to identify and characterise the CD37 antigen in cell labelling, indirect immunofluorescence and IP analysis (Link, 1986). In particular, the use of this antibody to label malignant B cells indicates that expression of CD37 occurs relatively late in B cell maturation, as it is not expressed on "immature" B lineage lymphoid neoplasms.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD37

Antigène: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Autre désignation: CD37

Sujet: Tetraspanin-26, Tspan-26, Leukocyte antigen CD37,

UniProt: P11049

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response