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Recombinant EGFR (Nimotuzumab Biosimilar) anticorps

Cet anticorps Human Monoclonal détecte spécifiquement EGFR (Nimotuzumab Biosimilar) dans BR, FACS et IHC. Il présente une réactivité envers Humain.
N° du produit ABIN7072381

Aperçu rapide pour Recombinant EGFR (Nimotuzumab Biosimilar) anticorps (ABIN7072381)

Antigène

EGFR (Nimotuzumab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 1
  • 1
  • 1
  • 1
Human

Clonalité

  • 3
  • 1
Monoclonal

Conjugué

  • 4
Cet anticorp EGFR (Nimotuzumab Biosimilar) est non-conjugé

Application

  • 2
  • 2
  • 2
  • 1
Blocking Reagent (BR), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone

H-R3
  • Fonction

    Anti-EGFR domain III [h-R3 (Nimotuzumab)], Human IgG1, kappa

    Specificité

    Binds to human EGFR domain III at a site distinct from antibody 7A7 (Ab00134) (Talavera et al. 2011)

    Attributs du produit

    Original Species of Ab: Human

    Original Format of Ab: IgG1

    Purification

    Protein A affinity purified

    Immunogène

    This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors.

    Isotype

    IgG1 kappa
  • Indications d'application

    This antibody binds to human EGFR and inhibits EGF-dependent clonogenic growth of NRK cells and completely blocks EGF stimulated autophosphorylation of the receptor (Fernandez 1992)

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Antigène

    EGFR (Nimotuzumab Biosimilar)

    Classe de substances

    Biosimilar

    Sujet

    ERBB-D3, ERBB1, HER1, PIG61, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1, epidermal growth factor

    UniProt

    P00533
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