Recombinant CD276 anticorps (Extracellular Domain)

N° du produit ABIN7072434

Cet anticorps anti-CD276 est un anticorps Lapin Chimeric détectant CD276 dans FACS et BR. Adapté pour Souris.

Aperçu rapide pour Recombinant CD276 anticorps (Extracellular Domain) (ABIN7072434)

Antigène: CD276

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD276 est non-conjugé

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Clone: MJ18

Détail du produit anti-CD276 anticorps

Épitope: AA 1-242, Extracellular Domain

Fonction: Anti-B7-H3 [MJ18], Rabbit IgG, kappa

Specificité: This antibody binds to mouse B7-H3 and does not react with other B7-family molecules.

Attributs du produit:

Original Species of Ab: Rat

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1-242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD276

Antigène: CD276

Autre désignation: B7-H3

Sujet: CD276, B7H3

UniProt: Q8VE98

Pathways: Cancer Immune Checkpoints