Recombinant Interleukin 17a anticorps

N° du produit ABIN7072560

Cet anticorps anti-Interleukin 17a est un anticorps Souris Monoclonal détectant Interleukin 17a dans ELISA et BP. Adapté pour Souris.

Aperçu rapide pour Recombinant Interleukin 17a anticorps (ABIN7072560)

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Interleukin 17a est non-conjugé

Application: ELISA, Blocking Peptide (BP)

Clone: MM17F3

Détail du produit anti-Interleukin 17a anticorps

Fonction: Anti-IL-17A [MM17F3], Mouse IgG1, kappa

Specificité: This antibody is highly specific for murine IL-17A, in ELISA analysis, no cross-reactivity with IL-17B, IL-17C, IL-17D, IL-17E or IL-17F was observed.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: This antibody was raised by immunising C57Bl/6 mice with IL-17A cross-linked to ovalbumin to generate a highly immunogenic complex.

Isotype: IgG1 kappa

Information d'application

Indications d'application: The specificity of this antibody has been confirmed in ELISA analysis (Uyttenhove et al, 2006). This antibody inhibits IL-17A-induced IL-6 production by a Cl1D fibroblastic cell line in vitro (Uyttenhove et al, 2006). This antibody has been shown to prevent experimental autoimmune encephalomyelitis (EAE) disease development in vivo (Uyttenhove et al, 2006), as well as protecting C57Bl/6 mice from myelin oligdendrocyte glycoprotein (MOG)-induced EAE (Uyttenhove et al, 2007). Additionally, administration of this antibody inhibits collagen-induced arthritis (CIA) in IFN-γ receptor knockout mice (Kelchtermans et al, 2009).

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur Interleukin 17a

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Autre désignation: IL-17A

Sujet: Interleukin-17A, IL17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8

UniProt: Q62386