Recombinant CD79b anticorps

N° du produit ABIN7072739

L’anticorps Lapin Chimeric anti-CD79b a été validé pour FACS, IHC, IP et IF. Il convient pour détecter CD79b dans des échantillons de Souris.

Aperçu rapide pour Recombinant CD79b anticorps (ABIN7072739)

Antigène: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD79b est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: HM79-16

Détail du produit anti-CD79b anticorps

Fonction: Anti-CD79b [HM79-16], Rabbit IgG, lambda

Specificité: Reacts with an extracellular epitope of CD79b.

Attributs du produit:

Original Species of Ab: Hamster, Armenian

Original Format of Ab: IgG2

Purification: Protein A affinity purified

Immunogène: HM79-16 was initially generated by purifying CD79b from WEHI231 B cells and used for immunisation of footpads of an Armenian hamster. Hybridoma supernatants were screened for positive reactivity in surface immunofluorescence of WEHI231 and then the specificity to CD79b was tested by immuno-precipitationRecombinant anti-CD79 antibodies were engineered by cloning and sequencing the full-length IG heavy and light chains of an Armenian hamster (Cricetulus migratorius).

Isotype: IgG lambda

Information d'application

Indications d'application: A biotinylated HM79-16 was used and stained with streptavidin-FITC for analysis by FACS to identify variants of B lymphoma cell lines that have lost expression of the mu heavy chain, and for staining using a biotinylated HM79-16 (Condon 2000). HM79-16 has also been used in competitive binding assays to study its effect on the binding of CD79a to CD79b in the context of ameliorating autoimmune disease in mice (Yongmei Li 2008).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Armenian Hamster IgG format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD79b

Antigène: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Autre désignation: CD79b

Sujet: Ig-beta, AGM6, B29, IGB, CD79b molecule,

UniProt: P15530

Pathways: BCR Signaling