WTX anticorps
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- Antigène Voir toutes WTX (AMER1) Anticorps
- WTX (AMER1) (APC Membrane Recruitment Protein 1 (AMER1))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WTX est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain, Rat
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Mouse FAM123B
- Top Product
- Discover our top product AMER1 Anticorps primaire
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anti-APC Membrane Recruitment Protein 1 (AMER1) (AA 681-708) antibody
AMER1 Reactivité: Humain, Souris WB, IHC (p), FACS Hôte: Lapin Polyclonal RB18795 unconjugated
anti-APC Membrane Recruitment Protein 1 (AMER1) antibodyAMER1 Reactivité: Humain, Souris ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-APC Membrane Recruitment Protein 1 (AMER1) antibodyAMER1 Reactivité: Humain, Souris IHC, WB, FACS Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB (H,M,R) 1: 500-1: 1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- WTX (AMER1) (APC Membrane Recruitment Protein 1 (AMER1))
- Autre désignation
- FAM123B (AMER1 Produits)
- Synonymes
- anticorps 2810002O09Rik, anticorps AW492303, anticorps Fam123b, anticorps Wtx, anticorps FAM123B, anticorps OSCS, anticorps WTX, anticorps RGD1560322, anticorps fam123b, anticorps APC membrane recruitment 1, anticorps APC membrane recruitment protein 1, anticorps Amer1, anticorps AMER1, anticorps amer1
- Sujet
- Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. Acts both as a positive and negative regulator of the Wnt signaling pathway, depending on the context: acts as a positive regulator by promoting LRP6 phosphorylation. Also acts as a negative regulator by acting as a scaffold protein for the beta-catenin destruction complex and promoting stabilization of Axin at the cell membrane. Promotes CTNNB1 ubiquitination and degradation. Involved in kidney development.
- Poids moléculaire
- 125 kDa
- ID gène
- 72345
- NCBI Accession
- NP_780388
- UniProt
- Q7TS75
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