ABCC3
Reactivité: Humain, Chien, Cobaye
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB (H,M,R) 1: 500-1: 1000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Antigène
ABCC3
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))
Autre désignation
MRP3
Sujet
The protein encoded by this gene is a member of the super family of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes.