Basonuclin 1 anticorps

N° du produit ABIN7073188

Cet anticorps anti-Basonuclin 1 est un anticorps Lapin Polyclonal détectant Basonuclin 1 dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Basonuclin 1 anticorps (ABIN7073188)

Antigène: Basonuclin 1 (BNC1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Basonuclin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Basonuclin 1 anticorps

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse BNC1/BNC

Information d'application

Indications d'application: WB (H,M,R) 1:250-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur Basonuclin 1

Antigène: Basonuclin 1 (BNC1)

Autre désignation: BNC1/BNC

Sujet: The zinc finger protein, basonuclin, is a putative rDNA transcription factor with highly restricted tissue distribution. Basonuclin is abundantly expressed in keratinocytes of the basal layer of the epidermis, the outer sheath of hair follicles and in the germ cells of the testis and ovary. In the epidermis, basonuclin, which is mainly localized to the cytoplasm, translocates to basal cell nuclei during different stages of keratinocyte growth. Basonuclin may enhance rRNA synthesis by elevating transcription from an rDNA promoter and inhibiting RNA polymerase I transcription through its zinc finger domain. Therefore, basonuclin may be a cell-type-specific transcription factor for rDNA transcription.

Poids moléculaire: 107 kDa

UniProt: O35914