BPTF anticorps
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- Antigène Voir toutes BPTF Anticorps
- BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BPTF est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Souris, Rat
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Human BPTF
- Top Product
- Discover our top product BPTF Anticorps primaire
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anti-Bromodomain PHD Finger Transcription Factor (BPTF) (AA 2801-3046) antibody
BPTF Reactivité: Souris, Rat WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
anti-Bromodomain PHD Finger Transcription Factor (BPTF) antibodyBPTF Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2F10 unconjugated
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- Indications d'application
- IHC/IF (H,M,R) 1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))
- Autre désignation
- BPTF/FALZ (BPTF Produits)
- Synonymes
- anticorps FAC1, anticorps FALZ, anticorps NURF301, anticorps 9430093H17Rik, anticorps Falz, anticorps BPTF, anticorps bromodomain PHD finger transcription factor, anticorps nucleosome-remodeling factor subunit NURF301, anticorps fetal alzheimer antigen, falz, anticorps BPTF, anticorps Bptf, anticorps LOC5576547, anticorps CpipJ_CPIJ011285, anticorps bptf
- Sujet
- FALZ/BPTF is a histone-binding component of NURF (nucleosome remodeling factor), a complex that catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. This gene was identified in brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), containing a DNA-binding domain, a zinc finger motif, and a C-terminal bromodomain, suggested it might play a role in the regulation of transcription during proliferation. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. This protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex. In Drosophila, the NURF complex, which catalyzes nucleosome sliding on DNA and interacts with sequence-specific transcription factors, is necessary for the chromatin remodeling required for transcription.
- ID gène
- 2186
- NCBI Accession
- NP_004450
- UniProt
- Q12830
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