Cathepsin L2 anticorps

N° du produit ABIN7073348

Cet anticorps Lapin Polyclonal détecte spécifiquement Cathepsin L2 dans IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Cathepsin L2 anticorps (ABIN7073348)

Antigène: Cathepsin L2 (CTSL2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin L2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Cathepsin L2 anticorps

Réactivité croisée: Souris, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Human Cathepsin V

Information d'application

Indications d'application: IHC/IF (H,M,R) 1:1000-1:2000/1:300-1:600

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur Cathepsin L2

Antigène: Cathepsin L2 (CTSL2)

Autre désignation: Cathepsin V

Sujet: Cathepsin V is a lysosomal cysteine protease which has an important role in corneal physiology.Cathepsin V was found to be differentially expressed in relation to pigmentary skin backgrounds, and was about 7.5-folds higher in keratinocytes from lightly pigmented, relative to darkly pigmented skins. It is expressed in primary keratinocytes, melanocytes, and HaCaT keratinocytes, but not in primary fibroblasts. The purified cathepsin L2 was a high molecular weight proteinase of about 78 kDa, but it was unstable to SDS and reducing conditions, which dissociated parts of the proteinase into 66 kDa, 31 kDa and 26 kDa fragments(Food Chemistry,Volume11,Issue4,879-886) and it can form a complex of 70 kDa with an unidentified subunit.

ID gène: 1515

NCBI Accession: NP_001188504

UniProt: O60911

Pathways: Toll-Like Receptors Cascades