CHMP1A
Reactivité: Humain, Souris
WB, ELISA, IHC, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB (H,M,R) 1:500-1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Antigène
CHMP1A
(Charged Multivesicular Body Protein 1A (CHMP1A))
Autre désignation
CHMP1a
Sujet
Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein PCGF4/BMI1 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing.