CMA1 anticorps

N° du produit ABIN7073506

Cet anticorps anti-CMA1 est un anticorps Lapin Polyclonal détectant CMA1 dans IHC et IF. Adapté pour Souris et Rat.

Aperçu rapide pour CMA1 anticorps (ABIN7073506)

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CMA1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CMA1 anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse Chymase

Information d'application

Indications d'application: IHC/IF (M,R) 1:1000-1:2000/1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CMA1

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Autre désignation: Mast Cell Chymase

Sujet: This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.

ID gène: 17228

NCBI Accession: NP_034910

UniProt: P21844

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis