Thymidine Phosphorylase anticorps (AA 121-220) (Cy5.5)

N° du produit ABIN704446

Cet anticorps Lapin Polyclonal détecte spécifiquement Thymidine Phosphorylase dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Thymidine Phosphorylase anticorps (AA 121-220) (Cy5.5) (ABIN704446)

Antigène: Thymidine Phosphorylase (TYMP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thymidine Phosphorylase est conjugé à/à la Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Thymidine Phosphorylase anticorps (Cy5.5)

Épitope: AA 121-220

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Thymidine Phosphorylase

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Thymidine Phosphorylase

Antigène: Thymidine Phosphorylase (TYMP)

Autre désignation: TP/thymidine phosphorylase

Sujet:

Synonyms: ECGF 1, PDEGF, ECGF1, Endothelial cell growth factor 1, Endothelial cell growth factor 1 platelet derived, Gliostatin, hPD ECGF, MNGIE, PD ECGF, PDECGF, PDEGF, Platelet derived endothelial growth factor, TdRPase, TP, TYMP, Thymidine Phosphorylase, TYPH_HUMAN, TdRPase.

Background: In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

ID gène: 1890

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2