Thymidine Phosphorylase anticorps (AA 121-220) (HRP)

N° du produit ABIN704450

L’anticorps Lapin Polyclonal anti-Thymidine Phosphorylase a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter Thymidine Phosphorylase dans des échantillons de Humain.

Aperçu rapide pour Thymidine Phosphorylase anticorps (AA 121-220) (HRP) (ABIN704450)

Antigène: Thymidine Phosphorylase (TYMP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thymidine Phosphorylase est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Thymidine Phosphorylase anticorps (HRP)

Épitope: AA 121-220

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Thymidine Phosphorylase

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Thymidine Phosphorylase

Antigène: Thymidine Phosphorylase (TYMP)

Autre désignation: TP/thymidine phosphorylase

Sujet:

Synonyms: ECGF 1, PDEGF, ECGF1, Endothelial cell growth factor 1, Endothelial cell growth factor 1 platelet derived, Gliostatin, hPD ECGF, MNGIE, PD ECGF, PDECGF, PDEGF, Platelet derived endothelial growth factor, TdRPase, TP, TYMP, Thymidine Phosphorylase, TYPH_HUMAN, TdRPase.

Background: In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

ID gène: 1890

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2